Chronic Leg Swelling and a Possible Link to Chronic Vein Disease

Many factors can lead to lower extremity swelling. In very broad terms, there are 2 factors involved with fluid regulation within the lower extremities:

  • Factors affecting the outward/inward pressure against the walls of the veins.
  • Factors affecting the proteins inside blood vessels that help to “trap” water inside the vessels and decrease the tendency from water “leaking” out.